Twenty-year-old Danish participant Holger Rune recorded his second victory over Novak Djokovic in little greater than six months, beating the 22-time Grand Slam champion 6-2, 4-6, 6-2 Wednesday to succeed in the Italian Open semifinals.

Rune, who additionally defeated Djokovic within the Paris Masters remaining in November, gave the Serb suits along with his speedy court docket protection. He made his opponent hit additional balls on factors that Djokovic thought he had already completed off.

“This is probably the coldest and wettest tournament I’ve ever played here in Rome,” Djokovic stated. "In these form of situations, it’s very tough to get the ball previous him. He’s very, very quick, very fast. Great anticipation. Just a really gifted, dynamic participant, all-around participant.

“He was just better. He played too good for me for most part of the match,” Djokovic stated. “He kept his nerves and deserved to win.”

The 35-year-old Djokovic didn’t seem at his greatest bodily early on and referred to as for a coach after holding for a 2-1 lead within the second set. It wasn’t instantly clear what the difficulty was but it surely appeared that Djokovic swallowed a capsule that the coach gave him.

Djokovic not too long ago returned after three weeks off due to a lingering situation along with his surgically repaired proper elbow. He’s making ready for the French Open, which begins in 11 days.

“I know I can always play better,” Djokovic stated. “I always like my chances in Grand Slams against anybody on any surface, best-of-five. Let’s see how it goes.”

Rune, in the meantime, is boosting his credentials as a Grand Slam contender after a strong season on clay that included a runner-up end within the Monte Carlo Masters, a title in Munich, and now a semifinal spot in Rome in his first principal draw look.

“Every match is a huge challenge for me when I play against Novak. He’s obviously one of the greatest that ever played the game,” Rune stated. “I’m a huge fighter on the court and I leave everything when I play my matches."

Djokovic stormed out to a 5-2 lead in the second but Rune rallied back, winning a 34-shot rally with a sublime backhand drop-shot winner to set up a key break.

Rune also called for a trainer late in the second set to have his right leg treated, shortly before the match was suspended because of rain with Rune serving to stay in the set at 4-5, 0-30.

After a suspension of more than an hour, Djokovic won two straight points to break Rune’s serve and take the second set. But Rune then broke Djokovic’s serve twice early in the third.

Djokovic committed 35 unforced errors to Rune’s 15, with 22 of those coming on his forehand.

Djokovic has won the Italian Open six times, including last year, and failed to reach the final only once in eight previous editions — when he was beaten by Rafael Nadal in the semifinals in 2018.

Nadal, who holds the record of 10 titles in Rome, is not playing as he remains hampered by a nagging hip injury, leaving his status for Roland Garros in question.

With Djokovic out of the draw, an 18-year streak of either him or Nadal playing in the Rome final ends.

Djokovic will also lose the No. 1 ranking to Carlos Alcaraz, another 20-year-old player, next week — even though Alcaraz was beaten by 135th-ranked Hungarian qualifier Fabian Marozsan in the third round on Monday.

Rune’s semifinal opponent will be either Casper Ruud or Francisco Cerundolo, who were scheduled to play later.

In the women’s quarterfinals, two-time defending champion Iga Swiatek was up against Wimbledon champion Elena Rybakina and 2017 French Open champion Jelena Ostapenko was facing Paula Badosa.

Rune, who is known for his fiery behavior, got into a heated exchange with the chair umpire about a disputed call during the second set. When the umpire refused to change the call despite Rune saying that the mark on the clay showed that Djokovic’s shot was out, he lost his cool.

“Do you get punished when you make mistakes? You don’t. So please respect the player,” Rune stated to the umpire, Mohamed Lahyani. “It’s an absolute joke.”

As Rune’s coach, Patrick Mouratoglou, motioned from the stands for his participant to relax, Rune then stated to no person particularly, “It’s always the umpire who makes me look like the bad guy.”

Early within the third, Djokovic grew pissed off with Lahyani due to the way in which he was saying the rating between Italian and English, and when the service shot clock began.

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Andrew Dampf is at https://twitter.com/AndrewDampf

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AP Tennis: https://apnews.com/hub/tennis and https://twitter.com/AP_Sports