Robert De Niro's 19-year-old grandson Leandro De Niro Rodriguez died after being offered fentanyl-laced drugs, his mom has stated.

The actor's eldest daughter, Drena De Niro, announced Leandro's death on Monday, saying the household had misplaced a "sweet angel" - however a explanation for demise was not shared on the time.

But later replying to an Instagram remark asking how her son had died, the 51-year-old wrote: "Someone sold him fentanyl laced pills that they knew were laced yet still sold them to him.

"So for all these folks nonetheless f****** round promoting and shopping for this s***, my son is gone perpetually."

Sky News has approached the New York City medical expert's workplace for remark.

Representatives for De Niro didn't instantly reply to a request from Sky News' US accomplice community NBC News for remark about his daughter's posts.

On Monday, De Niro stated in an announcement that he was "deeply distressed by the passing of my beloved grandson Leo".

"We're greatly appreciative of the condolences from everyone. We ask that we please be given privacy to grieve our loss of Leo," he added.

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A New York police spokesperson informed NBC News that police bought a 911 name at about 2:23 pm on Sunday.

Officers discovered a person "unconscious" and "unresponsive", and he was pronounced lifeless by emergency companies.

"The Office of the Chief Medical Examiner will determine the cause of death," the spokesperson added.

Leandro adopted in his mom's and grandfather's footsteps in appearing.

He had small roles in A Star Is Born, The Collection and Cabaret Maxime.

De Niro adopted Drena as his daughter throughout his marriage with Diahnne Abbott. She was Abbott's daughter from her earlier marriage.