Rescuers are increasing their search into deeper waters as they hunt for a submersible that went lacking close to the wreck of the Titanic.

The US Coast Guard and different search and rescue crews have swarmed a distant space within the Atlantic in seek for the vessel, known as Titan, which went missing on Sunday with 5 individuals on board.

Coast Guard Rear Admiral John Mauger advised CNN: "As we continue on with this search ... we've been working through the night with a broad group of partners to bring all capabilities to bear looking on both the surface and now expanding to a subsurface in the area."

NATO rescue vessel cannot reach required depths - missing Titanic sub latest

Rescuers face a race against time to search out the lacking submersible as its oxygen provide dwindles.

It is known from the vessel's operator, OceanGate Expeditions, Titan had a 96-hour oxygen provide in case of emergencies - that means the individuals on board have round two days of "life support" left.

The 5 individuals on board are British billionaire Hamish Harding, Pakistani businessman Shahzada Dawood and his son Suleman, chief govt and founding father of OceanGate Expeditions Stockton Rush, and French submersible pilot Paul-Henri Nargeolet.