A Russian bomb has hit a blood transfusion centre within the Ukrainian area of Kharkiv, Volodymyr Zelenskyy has claimed.
On Telegram, the Ukrainian president mentioned there are fatalities and accidents after the strike within the city of Kupiansk.
Mr Zelenskyy mentioned rescue employees have been extinguishing fires on the scene, and he described the assault as a "war crime".
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Kupiansk is a railway hub that's fewer than 10 miles from the frontline - and at this level, it's unclear how many individuals have been killed or wounded.
Russia has beforehand denied concentrating on civilians in a full-scale invasion that has killed 1000's of individuals, uprooted tens of millions and destroyed cities.
Throughout Saturday, explosions and air alerts have been reported throughout Ukraine - together with within the capital of Kyiv.
It comes after Russia's defence ministry warned of retaliation following drone assaults on ships within the Black Sea.
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A tanker transporting fuel for Putin's forces was hit on Friday evening by a sea drone that was full of 450kg (992lbs) of TNT - and a significant port was focused earlier within the day.
"There can be no justification for such barbaric actions, they will not go unanswered and their authors and perpetrators will inevitably be punished," spokeswoman Maria Zakharova mentioned.
In different developments, Ukraine has reportedly used cluster monitions within the Russian-occupied metropolis of Donetsk - with a college on fireplace.
The controversial weapons are banned in additional than 120 international locations as a result of they've a observe document of killing and maiming civilians.
They detonate within the air and releases "bomblets" that scatter over a big space, however smaller munitions can fail to detonate and pose a long-term threat to civilians.
Cluster bombs have been equipped to Ukrainian forces by the US.
President Joe Biden mentioned the controversial resolution was a "difficult" one - however he needed to act as a result of Mr Zelenskyy's forces have been operating out of ammunition.
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